Clinical case 2

I'm not a clinician but from laboratory scientific point of view here are my comments for discussion.

It would be important to have at least some of the ovarian tissue assessed for histopathology together with any potenial immunohistochemical markers before making any recomemdation regarding transplantation. Although this is a limited sample assessment and can not guarantee the tissue transplantation would be free of malignancy, this should be undertaken for every patient thinking of having transplantation.

A site for transplantation where the tissue can be easily removed and monitored is important. Our teams experience with transplantation to an intrapertoneal abdominal site (Gook 2021) has shown this to be a suitable site for ovarian function and could be a possible site, if the case is recommended for transplantation.